Written by: The Midland Certified Reagent Company
Summary: Purified oligos offer scientists the chance to work on groundbreaking research.
The process of synthesizing DNA molecules has been fully automated since the 1970s. Oligos are used heavily in modern research, and high quality oligos make a huge difference in the final reaction. Ever-increasing pressure on research institutes to deliver actionable data means that there is a huge demand for faster turnaround times and cheaper solutions.
Efficiency in the Lab
If you were trying to test the potential yield of an oil field, for instance, you would need to test for whether the market will buy the oil at a higher or lower value. Modified oligonucleotides would allow researchers to test for specific reactions, which would help determine how marketable oil would really be.
Increasingly, that process is becoming faster and more affordable. That’s helping us learn more about life too. A molecular beacon probe is a modified oligonucleotide that is like a tracker. It hunts for specific nucleic acids, which could signal how a species evolved in the case of SNP genotyping.
Cost-Efficient Experimentation
Science relies on the ability to test new ideas, but testing costs can quickly add up. A pharmaceutical company can easily devote a majority of its revenue back into testing. Failing an experiment due to a poor oligo is a huge disappointment under such tight budgets and deadlines.
Once the treatments come to the public, there are measures in place to keep costs relatively low. It’s common knowledge that new technology decreases in value over time, but in vitro processes consistently utilize phosphorothioate oligonucleotides.
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